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Treatments for Cardio Vascular Disease- Angina

December 30, 2013 Helth Comments Off on Treatments for Cardio Vascular Disease- Angina

Angina or Angina pectoris which is cardio vesicular disease also known simply as chest pain. It occurs if an area of your heart muscle doesn’t get enough oxygen-rich blood. Angina may feel like pressure or squeezing in your chest. The pain also can occur in your shoulders, arms, neck, jaw, or back. Angina pain may even feel like indigestion. Treatments for cardio vascular disease are described here.

Types of Angina

  • Stable angina. The pain is predictable and present only during exertion or extreme emotional distress, and it disappears with rest.
  • Unstable angina. This may signal an impending heart attack. Unstable angina is angina pain that is different from your regular angina pain or pain that occurs while at rest. The angina may occur more frequently, more easily at rest, feel more severe, last longer, or come on with minimal activity. Although this type of angina can often be relieved with medication, it is unstable and may progress to a heart attack. Usually more intense medical treatment or a procedure is required.
  • Prinzmetal’s angina. This is when angina occurs at rest, when sleeping, or when exposed to cold temperatures. In these cases, the symptoms are caused by decreased blood flow to the heart muscle from a spasm of the coronary artery. The majority of people with this type of angina also have coronary artery disease. These spasms occur close to the blockage.
  • Microvascular angina. This is also known as  Angina Syndrome X is characterized by angina-like chest pain, but the cause is different. The cause of Microvascular Angina is unknown, but it appears to be the result of spasm in the tiny blood vessels of the heart, arms and legs. Since microvascular angina is not characterized by arterial blockages, it is harder to recognize and diagnose, but its prognosis is excellent.

Drugs used for Angina

Glycerine Tri Nitrate (GTN)


  1. Prevention and treatment of angina
  2. Management of IHD
  3. To treat acute cardiac failure


  1. Very unstable can react with air, light,heat and material such as paper, polythene, wooding…ect
  2. Can tolerance when continuous or frequent administration
  3. Once open the container should not use beyond 8 weeks.

Contra indicationsAreas affect for angina

  • marked anaemia
  • closed angle glycoma

Side effect

  • headache
  • dizziness faintness
  • hypotention


Subingually: 0.3 mg to 1.0 mg repeated as required.(6 mg/day) [Keep under the tongue and allow to dissolve]

IV infusion:  10 µg-200 µg/minute cardiac failure , myocardial infaction

Dosage forms

  1. Glycerine tri nitrate 0.5 mg tablet for sublingual use
  2. Glycerine tri nitrate injection 50 mg/10.0 ml ampoules

Iso Sorbide Di nitrate


  1. Management of  IH and Angina
  2. To treat acute cardiac failure
    Angina PectorisAngina Pectoris


  1. Tolerance – can be avoid drug free intervals

Side effect – Same as GTN


By mouth 30 mg -120 mg d.d.d fro angina

40 mg-160 mg up to 240 mg d.d.d. for left ventricular failure IV infusion 2 mg-10 mg /hour

Dosage forms

Iso sorbide di nitrate 10 mg tablet

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Summary of "Treatments for Cardio Vascular Disease- Angina"

Angina pectoris which is cardio vesicular disease. Two types of drugs use for treat for angina. Treatments for cardio vascular disease are described here.

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